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De la Morena E et al
Dysregulation of KEAP1-NRF2 activity has been extensively demonstrated in cellular and animal models of ALS and in postmortem ALS motor cortex and spinal cord samples, so dysregulation of the NRF2/ARE antioxidant and cytoprotective pathway could be a possible mechanism underlying the progressive neurodegeneration in ALS and severity of the disease
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This situation is a conundrum since homology with human regulatory subunit has been found for a great number of fungi, in particular with those from genus Aspergillus and Penicillium, ascomycetes like C
It helps in maintaining even skin tone and assists in the management of blemishes, dark spots, and pigmentation
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