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doi:10.1007/s00018-017-2609-7

reported the general paradigm that the elevated energy metabolism in ovarian cancer cell lines was directly associated with increased lactate levels ( et al

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Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism

This should be used in conjunction with other known methods of combating fatigue, such as losing weight, reducing stress, drinking less alcohol, and trying to partake in more physical activities

When used together they may have synergistic effects and give more muscle mass, fat loss and bone health than either compound alone