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Many find satisfactory results at 4-8mg weekly, significantly reducing both cost and vial requirements

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Most patients can expect 1525% total body weight loss over 1218 months, especially when paired with nutrition and activity changes

The most striking protective effects of SGLT2is were a marked reduction in hospitalization for heart failure and a remarkable reduced progression of chronic kidney disease

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However, clinical outcomes are complicated by behavioral factors, including lower adherence rates reported among women, which may obscure the true extent of sex-related efficacy differences [52]