On the other hand, compounded tirzepatide may contain additional ingredients such as vitamin B-12, vitamin B-6, L-carnitine, and othersthat are not found in Zepbound
While their name may cause people to assume they are patches containing semaglutide, tirzepatide or another GLP-1 drug, it is worth noting that the currently available GLP-1 patches contain herbal supplements, not GLP-1 agonist drugs
The authors found that GLP-1 RA use was associated with a significantly decreased risk of developing dry AMD compared with patients taking metformin (HR = .68), insulin (HR = .72), and statins (HR = .70)
While older drugs focused on one pathway, tirzepatide engages both GLP-1 and GIP pathways simultaneously
For a side-by-side of how this compares to the dual and single agonists, see our breakdown of Retatrutide vs Semaglutide vs Tirzepatide