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Whether any of that holds is a question about evidence, and the evidence is genuinely contradictory rather than merely thin

PT-141 is contraindicated in patients with uncontrolled hypertension

Standard practice involves rotating injection sites among convenient locations (abdomen, thighs, upper arms) to prevent tissue damage while achieving systemic distribution

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It might be useful for prevention of breast cancer in women at high risk

While supporters argue that regulated compounding could bring greater oversight to a largely grey-market sector, critics continue to question whether the available evidence supports wider clinical use