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In a 56-week clinical trial, people taking Saxenda 3 mg once a day lost an average of 18 lbs, while those using a placebo injection only lost 8 lbs

Some patients experience a temporary increase in GI symptoms when they step down, possibly related to rebound gastric motility changes

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20 Similar findings were also reported for men

Clinical research has shown that, when combined with a reduced-calorie diet and increased physical activity, semaglutide can lead to significant weight loss