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All animals were housed under controlled temperature and a 12-hour lightdark cycle, with ad libitum access to food and water
According to OBRA, the use of antidiabetic medications should include monitoring (e.g., periodic blood glucose) for effectiveness based on desired goals for that individual and to identify complications of treatment such as hypoglycemia or impaired renal function
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Manning NJ, Davies NP, Olpin SE, Carpenter KH, Smith MF, Pollitt RJ, Duncan SL, Larsson A, Carlsson B: Prenatal diagnosis of glutathione synthase deficiency
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Moreover, due to their ability to slow gastric emptying, these drugs may compromise the effectiveness of oral medications
