Clinical trial data show considerable individual variation in response, with some patients losing substantially more weight than the average while others experience more modest results
These reflect either elevated cardiometabolic risk (prediabetes) or established cardiovascular disease (prior heart attack, prior stroke, symptomatic PAD)
For example, the highest maintenance dose of Wegovy is 2.4 mg, with the lowest dose 0.25 mg
89% of adults taking Wegovy HD lost 5% or more of their body weight in a separate clinical study
I will also incorporate my knowledge on Novo Nordisk in this analysis, as I think to fully comprehend Eli Lilly, you have to understand Novo Nordisk as well
Diabetes 68(6):11211129 Grespan E, Giorgino T, Natali A, Ferrannini E, Mari A (2021) Different mechanisms of GIP and GLP-1 action explain their different therapeutic efficacy in type 2 diabetes