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However, IGF1 has no significant impact on muscle mitochondrial function, indicating that the deficiency of IGF1 in male mice has different roles on tissue mitochondrial function between the center and periphery circulation (Pharaoh et al., 2020)

However, this is not the primary mechanism of weight loss

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Unlike growth factors that act on single receptor families, BPC-157 operates through a multi-pathway convergence that makes it uniquely effective across tissue types