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doi: 10.1038/s41576-025-00907-1 323 TianG.ChenH.JiangR.ZhangC.LuX.WangX.et al
Because retatrutide affects several pathways in the body, its dosing requires careful management
In this study, a mean weight reduction of 7.8 percent, 9.3 percent, and 12.4 percent was reported at 6, 12, and 36 mg, versus 2.1 percent under placebo
Below BMI 27, prescribing is off-label, and Second Nature doesnt prescribe medications to anyone with a BMI of below 27
The drug semaglutide, sold as Ozempic, is marketed as a treatment for diabetes, but can also be used to treat obesity
Then, reduce to 1 injection weekly for maintenance
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