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Peptidases, such as DPP4, are known to regulate functional activity of chemokines

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[21] A randomized, double-blind, placebo-controlled study on oral glutathione supplementation (500 mg twice daily for four weeks) in 40 healthy adult volunteers failed to show any significant change in serum glutathione levels

Additional studies indicate that GHK may neutralize hydroxyl and peroxyl radicals in vitro and may limit iron release from ferritin in model systems, suggesting a route to reduced peroxidative stress

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