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[8] [9] [10] [11] Although reduced GLP-1 secretion has previously been associated with attenuated incretin effect in patients with type 2 diabetes, further research indicates that GLP-1 secretion in patients with type 2 diabetes does not differ from healthy subjects

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Animals in the LOsG and sham groups ( n = 10 in both groups) were given 6 g/kg glucose and distilled water (2 mL/100 g body weight), respectively, by gavage every 6 h for 6 weeks