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At baseline, 57% of the population had diabetes mellitus more than 5 years and had a mean hemoglobin A1c (HbA1c) of 8%

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As their use expands globally, it becomes increasingly important to evaluate all components of these therapies, not just the active compound." Story Source: Materials provided by Adelaide University

However, more data are needed to assess whether gastric emptying will be more affected by GLP1RAs in patients with pre-exposure gastric motility disorders, and whether it might result in clinically significant PK changes

This is usually a gradual, subtle shift rather than a dramatic change

If your interest in GLP-1 therapy relates to these emerging indications, frame the conversation accordingly