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doi: 10.1111/dom.14843, 53 GibbonsC.BlundellJ.Tetens HoffS.DahlK.BauerR.BaekdalT
Circulation: Heart Failure, 17 (4), Article e011351
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However, AR variants such as AR-V7 and ARv567es lack the entire LBD or a functional LBD, but retain their ability to bind DNA in the absence of androgens and display constitutive activity, thus conferring drug resistance to next-generation AR inhibitors