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These exposures act via a mechanism involving hormonal dysregulation, oxidative stress buildup, DNA damage, and epigenetic alterations

Chen R, Armamento-Villareal R

Very rarely, symptoms may include: Eye problems Abnormal blood clotting Skeletal problems Learning difficulties MTHFR gene mutation physical signs There are usually no physical signs of this mutation

Popovic M, Warr DG, Deangelis C, Tsao M, Chan KK, Poon M, Yip C, Pulenzas N, Lam H, Zhang L, Chow E

Another more comprehensive meta-analysis, which included 29 studies, indicated that the sensitivity and specificity reached 80% and 88%, respectively

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