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Arterioscler Thromb Vasc Biol 36(10):20482057 Ebnet K, Aurrand-Lions M, Kuhn A, Kiefer F, Butz S, Zander K et al (2003) The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity
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The mechanisms underlying mitochondrial dysfunction include excessive generation of mitochondrial ROS (mtROS), loss of mitochondrial membrane potential, release of (mtDNA into the cytoplasm, and dysregulation of mitochondrial dynamics such as fission and fusion (Monzel et al., 2023)