Preclinical research evidence Animal Experiments Obese mouse model: After subcutaneous injection of AOD 9604 (250 g/kg) daily for 8 weeks, the body weight of obese mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue decreased significantly
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While this does not guarantee human safety, it provides encouraging preliminary data
The injectable form provides systemic effects while topical application targets specific areas directly
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Nevertheless, cystine is taken up by some cells (i.e., endothelial cells) and, given the high reducing conditions, is intracellularly reduced to cysteine, employed for the synthesis of GSH (10, 11)