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Aulinger BA, Vahl TP, Prigeon RL, DAlessio DA, Elder DA

The incomplete inhibition of ER stress by targeting canonical ER stress sensor proteins suggests the existence of noncanonical ER stress pathways in ALD pathology

All animal experiments were approved by the Institutional Animal Care and Use Committee of the College of Medicine at Gachon University (approval number: LCDI-2020-0135)

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Further mechanistic investigations are warranted to clarify the exact mechanisms mediating the synergistic effect of L-carnitine and synbiotic combined therapy on weight and metabolic parameters. Source: Frontiers in Endocrinology Ameliorating effects of L-carnitine and synbiotic co-supplementation on anthropometric measures and cardiometabolic traits in women with obesity: a randomized controlled clinical trial Authors: Farnoush Fallah, et al .