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Cardiologist Dr
Weight outcomes varied depending on why the medication was originally prescribed
NICE guidance provides clear recommendations for GLP-1 use, which focus exclusively on glycaemic control in type 2 diabetes (NG28) and weight management in obesity (TA875 for semaglutide, TA664 for liraglutide)
GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the intestines and plays a key role in regulating blood sugar levels and controlling appetite
Semaglutide is a GLP-1 receptor agonist that, for many patients, provides sufficient appetite control and weight loss support without needing the dual-agonist approach that tirzepatide offers
This structural difference explains their divergent research profiles
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