Six studies have evaluated the effects of the mimetics, exenatide (86, 108, 109, 134) or liraglutide (79, 109)
GLP-1 RAs are chronic medications for long-term use
Concurrent application with highly acidic or strongly chelating topical agents-such as concentrated ascorbic-acid serums-may reduce the activity of one or both products because copper ions can catalyze oxidation reactions
We do not yet have evidence that they're safe for people without obesity, diabetes, and/or cardiometabolic disease
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For example, Novo Nordisks latest quarterly financial results showed like-for-like revenue down 4% year on year at constant exchange rates, even though their GLP-1 sales for obesity treatment rose by more than 20%