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S., Cho, W

S.et al (2021)

Depigmentation and/or subcutaneous atrophy can occur in thin patients, especially those with dark skins, and they should be informed of this before giving consent

With the standard 4mm needles, most patients can inject at a 90-degree angle without pinching the skin

Beyond routine glucose and lipid panels, endocrine studies increasingly include microbiome profiling, bile-acid pools, and hepatokine/adipokine panels (FGF21, adiponectin) to explain shifts in substrate preference

While this effect can be desirable for weight loss, it may also lead to inadequate nutrient intake if not monitored carefully