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DSIP was first isolated in 1977 from the cerebral venous blood of rabbits during induced sleep by a Swiss research group

Increased infarct size and exacerbated apoptosis in the glutathione peroxidase-1 (Gpx-1) knockout mouse brain in response to ischemia/reperfusion injury

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These activities decrease oxidative damage markers, which frequently relates to increased motility and decreased DNA fragmentation scores

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