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Causal Relationships Among the Gut Microbiome, Short-Chain Fatty Acids and Metabolic Diseases

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The reduction in steatosis in the GLP-1R agonist-treated group was accompanied by suppressed expression of hepatic genes for de novo lipogenesis ( Acc1 , Srebp1c and Fasn ), for reactive oxygen stress ( Nrf2 , Nox2 ) and inflammation ( Mpo , Il-6 , Il-12 ) (Fig

When appetite rebounds abruptly, rebound hunger can increase the likelihood of rapid weight regain