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doi: 10.1186/s12967-025-06927-z 30

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Benefits Beyond Weight Loss: Metabolic and Cardiovascular Health Cardiovascular risk reduction semaglutide reduced major cardiovascular events by 20% in the SELECT trial Blood sugar control significant HbA1c reductions in patients with type 2 diabetes or prediabetes Reduced liver fat growing evidence supports GLP-1 therapy for NAFLD and MASLD Sleep apnea improvement tirzepatide demonstrated 63% reduction in apnea-hypopnea index (2024 NEJM trial) Fatty Liver Disease & GLP-1 Therapy Patients with NAFLD/MASLD may see significant improvement with GLP-1 treatment

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Integrins display physical interaction with several extracellular matrix (ECM) glycoproteins (such as collagens, fibronectins, and laminins) and cellular receptors (Plow et al., 2000

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Young, L., Drugs that stimulate oxytocin release promote social bonding in an animal model relevant to autism

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[] In addition, improved sperm motility leads to higher fertilization rates, thus contributing to better fertility outcomes

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10.1038/s41586-021-03362-0 61 PortincasaP.KhalilM.MahdiL.PerniolaV.IdoneV.GrazianiA.et al (2024)

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