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PDP covers four weight management stacks: CagriSema (cagrilintide + semaglutide), Cagrilintide + Tirzepatide, Cagrilintide + Retatrutide, and Retatrutide + MOTS-c
El-Yamany MF, Zaki ES, Shaltout SA, Saad MA
For weight management in the UK, NICE-approved options are limited to orlistat (available over-the-counter or on prescription) and, within specialist weight management services, liraglutide 3.0mg (Saxenda) or semaglutide 2.4mg (Wegovy) with their specific continuation criteria
Pregnant or breastfeeding individuals No safety data exists for cagrilintide use during pregnancy or breastfeeding
Most patients begin with the 2.5mg dose for the first four weeks before advancing
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