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Augmented oxidative stress secondary to increased levels of interleukin-6 and tumor necrosis factor- in addition to decreased levels of interferons and are primarily believed to be the drivers of the disease process (Guloyan et al., 2020)

As disease onset neared, microglia expressed increased chemokine (CC motif) ligand 2 and other chemotaxis-associated molecules, which are involved in the recruitment of monocytes to the CNS by spinal cordderived microglia

Inhibition of cell death by blocking Src kinase (e.g., PPI)

Foods like egg yolk, peppers, and sweet yellow corn are good sources, too

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