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Activated Nrf2 promotes the gene expression of several antioxidant enzymes and proteins, such as superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione peroxidase (GPx), heme oxygenase-1 (HO-1), and NAD(P)H as a means of protecting the cells from oxidative stress and maintaining the dynamic balance between oxidation and antioxidant protection
A conservative dose of chromium picolinate, which is more absorbable than other forms, is included to protect against deficiency while avoiding excess
doi: 10.1111/j.1600-0625.2010.01125.x 174 RohdeBSchreinerHEVogelA
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10.3390/ijms25084284 157 VoelklJ.AlzoubiK.MamarA
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