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Similar shares of adults regardless of gender, income, or health insurance coverage report taking these drugs
The expected decrease in HbA1c is 0.71%,46 and sustained efficacy has been demonstrated in studies with up to fouryears of follow-up.47 Since their mechanism of action is insulin-independent, the SGLT2 inhibitors are effective in all stages of DM2 and do not cause hypoglycemia when administered in monotherapy
Rotating injection sites (abdomen, thigh, upper arm) and proper technique minimize these reactions
Data were performed in HEK293A cells stably expressing the GLP-1R, and are mean + s.e.m
In practice, generic entry typically reduces branded revenues by 60-90% within two years of the first generic launch, so the counterfactual revenue loss from full generic erosion is material
Holmberg KV, Hoffman MP
