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Patients with chronic kidney disease (eGFR below 60 mL/min/1.73m) have never been included in KLOW safety trials, so clearance patterns and potential accumulation of metabolic byproducts in that population are unknown

Alcohol consumption is a frequent concern

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The next cycle is at the provider and patient's discretion and based on overall goals for the treatment

Alexander Castro is a staff writer for the Rhode Island Current.

Literature search methodology This review was conducted through systematic searches of PubMed/MEDLINE, Scopus, and Web of Science, complemented by searches of specialized phytochemical databases (Dr