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Oral forms of calcium channel blockers are also available, but these generally result in less fissure healing and more side effects than topical treatment

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At $349 monthly cash-pay (or $199 for compounded semaglutide), these options cost 65% to 80% less than Mounjaro at retail, though with somewhat lower average weight loss (14.9% versus 22.5%)

Among those not taking the medications, 13% said they were likely to start in the future