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It has been hypothesised, based largely on data from tirzepatide studies, that GIPR agonism may moderate some of the gastrointestinal side effects associated with GLP-1R stimulation
Do not add training complexity while your body is adapting to the medication and the side effects are settling
The fatty acid chain allows reversible binding to albumin, dramatically extending circulation time
As Case 2 demonstrated, a patient may tolerate one drug in the class (semaglutide) but not another (tirzepatide), suggesting the reaction may be specific to certain agents or their unique pharmacologies
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