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Depletion of -glutamyl cyclotransferase suppresses the proliferation, migration and invasion of breast cancer cells accompanied by the activation of PI3K/AKT/mTOR pathway

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This reaction is catalyzed by glutathione peroxidase (GPx), producing oxidized GSSG, which is subsequently recycled back to GSH by glutathione reductase

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Sensory : pins and needles or numbness in feet and/or hands, or sometimes increased sensitivity to pain