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What exists is a strong pre-clinical foundation in rodents, a biologically plausible rationale for studying similar effects in dogs, and a clinical patient population that presents with the exact disease categories the rodent literature has focused on

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Also, a small cross-sectional study of 36 women with PCOS noted no changes in depression scores associated with liraglutide use over 6 months 204 , while another reported worsening depressive symptoms, which correlated with higher perceived stress scores, in 43 exenatide users with diabetes and obesity against non-users at 3 months 205

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