Symptoms Symptoms of EDS vary by type and may include: Back pain Double-jointedness Easily damaged, bruised, and stretchy skin Easy scarring and poor wound healing Flat feet Increased joint mobility, joints popping, early arthritis Joint dislocation Joint pain Premature rupture of membranes during pregnancy Very soft and velvety skin Vision problems Exams and Tests Examination by a health care provider may show: Deformed surface of the eye (cornea) Excess joint looseness and joint hypermobility Mitral valve in the heart does not close tightly (mitral valve prolapse) Gum infection (periodontitis) Rupture of intestines, uterus, or eyeball (seen only in vascular EDS, which is rare) Soft, thin, or very stretchy skin Tests to diagnose EDS include: Collagen typing (performed on a skin biopsy sample) Collagen gene mutation testing Echocardiogram (heart ultrasound) Lysyl hydroxylase or oxidase activity (to check collagen formation) Treatment There is no specific cure for EDS
10.1016/s0006-291x(72)80218-3 69 OhkawaH.OhishiN.YagiK
PMID: 35711368
Chemiluminescence was visualized on a scanner (Storm 860, Molecular Dynamics, Sunnyvale, CA) or using film
Discontinue use and seek medical attention if you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing
