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Among them, nine had low birth weight, defined as less than 2,500 g, and three had very low birth weight, defined as less than 1,500 g

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*Correspondence: Qilai Huang, [email protected] These authors contributed equally to this work This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In laboratory solutions, this aggregation makes it nearly impossible to maintain a monomeric, pharmacologically active preparation

Storing a peptide solution at 4 degrees Celsius instead of room temperature slows this hydrolysis substantially, because the reaction rate roughly halves for every 10-degree Celsius drop in temperature (Arrhenius kinetics)