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This disorder not only impacts fertility but also has significant effects on metabolic, reproductive, and cosmetic health

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The AF encapsulates the gelatinous NP, which is composed predominantly of type II collagen and elastin fibers that encase proteoglycan aggregates, of which aggrecan is most abundant

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Low iron can inhibit erythropoiesis through downregulating transferrin receptor expression on erythroid precursors, decreasing their ability to proliferate (Khalil et al 2018)