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Many people with low B12 feel fatigued and sluggish
The GRAS determination was likely based on the compound's limited systemic absorption (when ingested), short plasma half-life, and lack of acute toxicity signals in the Phase 2b obesity trial
B12 injections are simply a way for non-surgical weight loss patients to ensure they get adequate levels of B12 vitamin as it can be essential to losing weight in a healthy manner
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A patient info leaflet advises women to tell clinicians if pregnant, but also notes supplementing prevents deficiency risks
Additionally, adequate B12 levels have been linked in some studies to improved cardiovascular health through the reduction of homocysteine, a risk factor for heart disease
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