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Worsening of diabetic retinopathy with rapid improvement in systemic glucose control

Immune system failure could lead to uncontrolled replication of the SARS-CoV-2 virus, secondary infections and continuous shedding of the virus in patients who die from COVID-19 regardless of the time passed from the start of the infection (Ruan et al., 2020

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Once symptoms improve, a lower dose might be used