B12 supplements are often used to treat or prevent deficiency, which can lead to symptoms such as fatigue, weakness, constipation, loss of appetite, and megaloblastic anemia
Patskovsky YV, Huang MQ, Takayama T, Listowsky I, Pearson WR
The Effect of ProHydrolase on the Amino Acid and Intramuscular Anabolic Signaling Response to Resistance Exercise in Trained Males
This doesn't mean it is depleting your necessary hormone levels
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If it's not marketed as a whitening effect, people wont get the treatment because detoxifying your liver is not good enough for sales