In: Yadav AK, Shukla R, Flora SJS, editors
27 While a specific toxic metal has the potential to exert detrimental effects by select mechanisms, there are several common features among toxic heavy metals
Additionally, TPL-induced DNA damage (e.g., topoisomerase II inhibition causing double-strand breaks) and G1 phase cell cycle arrest ( via p21 upregulation and CDK suppression) exacerbate genomic instability and proliferation inhibition (Zhang H
No findings imply clinical relevance, therapeutic application, physiological effects, or suitability for human or veterinary use
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