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And results in one cancer type cannot be assumed to apply to others

Determining the appropriate dose and dosing regimen, for example, requires pharmaceutical companies to navigate a finely balanced set of variables to ensure a drug delivers the optimal effect with minimal impact on the patient

Patients with multiple moles, family history of melanoma, or a history of atypical nevi require specialist dermatological assessment before any melanocortin agonist is considered

Phosphoserine is subsequently converted to glycine via serine hydroxymethyltransferase (SHMT) (Fig