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Methods The systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement for traditional pairwise meta-analysis and the PRISMA extension for network meta-analysis.89 The study protocol was prospectively registered (PROSPERO CRD 42021271647)

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STEP Trials : These trials focused on the weight management aspect of GLP-1 therapy

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