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Discomfort when first starting the drug is normal
The company has indicated a strategic pivot toward "novel, non-commercial sequences for preclinical investigation" rather than commercially available GLP-1 and GIP compounds
Those fluctuations can be compounded by a variety of factors: stress, an imbalanced diet that doesnt prioritize protein, and a lack of focus on strength training
doi: 10.2337/db210459 44 CampbellJEDruckerDJ
However, nausea is a common side effect of GLP-1 therapy itself, especially during the first 48 weeks of treatment, so layering a cold illness on top of existing GLP-1 nausea can compound digestive discomfort and dehydration risk
[146] A number of orally available DPP-IV inhibitors are currently in clinical development and they seem to reduce the activity of DPP-IV by 75% or more, thereby increasing endogenous GLP-1 hormone concentrations
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