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Nat Commun 8 , 14835 (2017)

PLoS ONE 9 , e113234 (2014)

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

This is a good prerequisite for the intended in vitro reconstitution of the overall pathway

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Additionally, survival-rate analysis revealed a notable increase in therapeutic effectiveness, with 100% survival for wild-type mice over a 100-h period following a lethal dose of APAP when treated with the combination of hepsin and 200 mg/kg NAC