For example, in the SELECT cardiovascular outcome trial studying people with obesity, the extent of weight loss did not correlate with the effects of the drug to reduce heart attack, stroke, and cardiovascular death . Also, another long-acting GLP-1 therapy, albiglutide, [was] withdrawn from the market owing to modest efficacy for reduction of glucose and body weight in people with T2D
Regarding progress reviews , UK stopping rules for weight management pharmacotherapy are drug-specific
But even with this slow dose escalation, some people still find that the doses of traditional medicines are too high, resulting in uncomfortable side effects
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