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13 C NMR (100 MHz, DMSO-d 6 ) = 163.5, 162.4, 149.6, 149.6, 145.7, 139.3, 139.2, 126.0, 125.4, 116.6, 113.4

Furthermore, the molecular modeling demonstrates that the sulfur atom of T1 coordinating with the copper ions in the active site of tyrosinase is essential for mushroom tyrosinase inhibition and the ability of diminishing the human melanin synthesis

Tilton RG

Baselt, Disposition of Toxic Drugs and Chemicals in Man , 8th edition, Biomedical Publications, Foster City, CA, 2008, pp