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In MCF-7 and T47D cells, the Huaier extract combined with TAM can reduce cell viability and synergistically induce cell autophagy, apoptosis, and G0/G1 cell cycle arrest via the inhibition of the AKT/mTOR signaling pathway (Qi et al., 2016)

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Research Applications Investigation of melanocortin receptor signaling pathways Study of peptidereceptor binding and signaling dynamics Analysis of intracellular signaling mechanisms related to -MSH analogs Use in biochemical research models involving peptide-based signaling systems Key Features High-purity lyophilized research peptide (99%) Synthetic -MSH analog peptide structure Stable molecular profile suitable for laboratory research Designed for controlled biochemical and receptor signaling studies Content Compound: Melanotan II Form: Lyophilized powder Storage Information Store in a cool, dry place protected from light Refrigeration recommended for maximum stability Use within the recommended timeframe after reconstitution Research Use Only

It is a semisolid preparation designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients

PMID 24368434