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Hcty, homocysteine
Generally resolves over days to weeks with dose escalation
It tugs at you in the background of your day, and sometimes becomes so loud you can't ignore it
Phytother Res 2011;25(11):1721-1726
In a small clinical trial in patients with breast cancer taking tamoxifen 20-30 mg daily, adding curcumin 1200 mg plus piperine 10 mg three times daily reduces the 24-hour area under the curve of tamoxifen and the active metabolite endoxifen by 12.8% and 12.4%, respectively, as well as the maximum concentrations of tamoxifen, when compared with tamoxifen alone
Side effect Semaglutide Tirzepatide Nausea Very common during titration (~44%) Very common during titration (~3151%) Diarrhea / constipation Common (~30%) Common (~2333%) Vomiting Common (~24%) Common (~1326%) Discontinuation due to GI ~47% in trials ~58% in trials Muscle mass loss Significant without resistance training Similar
