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Peptides are short chains of amino acids that act as biological signaling molecules
Kong and Zheng 2020
Other risk factors that may increase vulnerability include: Long duration of diabetes (typically more than 10 years) Poor glycaemic control prior to starting GLP-1 therapy (HbA1c significantly above target) Rapid reduction in HbA1c (a drop of more than 2 percentage points [22 mmol/mol] within 36 months) Concurrent hypertension , especially if poorly controlled Diabetic kidney disease (nephropathy), which often correlates with retinopathy severity Previous history of retinal treatment (laser photocoagulation or intravitreal injections) People with type 2 diabetes but no retinopathy appear to have minimal risk of retinopathy progression based on current evidence
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and later the cell pellet was re-suspended in DMEM/HAMs F12 containing 10% fetal bovine serum (FBS) (Bio&Sell, Germany) culture media and was subjected to in vitro culture in a humidified 37 C, 5% CO 2 incubator
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