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These symptoms may indicate thyroid pathology requiring evaluation, though such occurrences are extremely rare

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Global disruption of Gclm results in mice (GCLM knockout) that have 15% of hepatic GSH levels seen in wild-type mice 16

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Common side effects include: Nausea and vomiting Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite (which, whilst an intended effect, can occasionally be excessive) Belching or indigestion Most of these effects are mild to moderate in severity and transient